Dose:response relationship – Medicine. Poison. Accreditation.


Consider these charts that show possible dose-response relationships of medicines.  Also of poisons.  Why has no similar research been done on the effects of accreditation?  Does that fact that is imposed by legislation and marketplace coercion imply that testing will show no benefit?

The cartel would like you to believe that accreditation produces the effect shown in B.

Dose–response relationships described by (A) the threshold model, (B) the linear non-threshold model, (C) the inverted U-shaped hormetic model and (D) the J-shaped hormetic model. (Adapted from Davis & Svendsgaard, 1990.)

I don’t think so.  Accreditation may improve a poor lab that would not thrive in a competitive market anyway.  For most, it impairs performance.  It would also impair profitability if it weren’t for the coercive aspect of accreditation being enforced by several mechanisms including legislation and misrepresentation. EQA scheme organisers have noticed a decline in labs’ performance when they become accredited.

Let’s see the research to prove which of the dose-response relationships applies to the record-keeping obsession.  Otherwise, let’s see the end of the inspection cartel that was founded as a home for redundant factory inspectors.

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This entry was posted in Cartel, Forensic science, Laboratory medicine, Medicine, Practical problems, Questions, Science and tagged , , , , , , , , , . Bookmark the permalink.

One Response to Dose:response relationship – Medicine. Poison. Accreditation.

  1. Reblogged this on Carlo Favaretti and commented:
    Provocatorio, ma utile per una riflessione critica.

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